| 高密度脂蛋白与心血管保护的研究进展 |
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| 引用本文： | 路英杰,杨雪,张旭昌,王晓云.高密度脂蛋白与心血管保护的研究进展[J].心脏杂志,2012,24(1):120-122. |
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| 作者姓名： | 路英杰 杨雪 张旭昌 王晓云 |
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| 作者单位： | 哈尔滨医科大学附属四院心内科一病房,黑龙江哈尔滨,150001 |
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| 摘 要： | 多项大规模临床研究显示,血清高密度脂蛋白(HDL)的水平与冠心病存在着密切的联系。HDL胆固醇对心血管的保护作用,体现在可介导胆固醇逆向转运、抗氧化作用、调节内皮功能、抗炎及影响凝血系统等。本文对HDL的结构和代谢进行了回顾,并对其心血管保护作用的新进展进行了综述。
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| 关 键 词： | 高密度脂蛋白 心血管保护 冠状动脉疾病 |
| 收稿时间： | 2011-06-30 |
Recent advance on high-density lipoprotein and its protection of cardiovascular disease |
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| LU Ying-jie,YANG Xue,ZHANG Xu-chang,WANG Xiao-yun.Recent advance on high-density lipoprotein and its protection of cardiovascular disease[J].Chinese Heart Journal,2012,24(1):120-122. |
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| Authors: | LU Ying-jie YANG Xue ZHANG Xu-chang WANG Xiao-yun |
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| Institution: | First Ward,Department of Cardiology,Fourth Affiliated Hospital,Harbin Medical University,Harbin 150001,Heilongjiang,China |
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| Abstract: | Many large-scale clinical studies show that high-density lipoprotein(HDL) level is closely related to coronary heart disease.Its cardiovascular protection is reflected in reversing cholesterol transport,anti-oxidation,adjusting endothelial function,anti-inflammatory,and exhibiting multiple beneficial effects on the coagulation system.In this paper,the structure and the metabolism of HDL as well as the progress on its protection of cardiovascular disease were reviewed. |
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| Keywords: | high-density lipoprotein(HDL) Cardiovascular protection Coronary artery disease |
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