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Malignant fibrous histiocytoma of the larynx
Authors:H. Kuwabara  K. Saito  T. Shibanushi  T. Kawahara
Affiliation:(1) Department of Pathology, Kagawa Medical School, 1750-1 Miki-cho, Kita-gun, 761-07 Kagawa, Japan;(2) Safety Research Laboratory, Kaken Pharmaceutical Co. Ltd., Shizuoka, Japan;(3) Department of Otorhinolaryngology, Kagawa Medical School, Kagawa, Japan
Abstract:Malignant fibrous histiocytoma of the upper respiratory tract is rare. We report a case of a glottic malignant fibrous histiocytoma in a 46-year-old man. Ultrastructural findings demonstrated that tumor cells were composed of fibroblast-like cells with abundant rough endoplasmic reticulum, histiocyte-like cells with numerous lysosomes and transitional cells with characteristics of both the fibroblast-like and histiocyte-like cells. Laryngeal microsurgery was performed as surgery and the patient has done well without recurrence to date (8 months after surgery).
Keywords:Malignant fibrous histiocytoma  Larynx Ultrastructural findings  Microsurgery
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