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治疗诱导性急性白血病(附1例报告)
引用本文:徐世荣,贾文娟. 治疗诱导性急性白血病(附1例报告)[J]. 河北医科大学学报, 1988, 0(1)
作者姓名:徐世荣  贾文娟
作者单位:河北医学院附属二院内科,河北医学院附属二院内科
摘    要:本文报告1例乳腺癌手术后病人,间断应用塞替派7年后发生继发性骨髓增生异常综合征(MDS),最后演变为急性白血病。复习文献,主要讨论了细胞毒药物致MDS及白血病转化的有关问题。

关 键 词:细胞毒药物  白血病  骨髓增生异常综合征(MDS)  乳腺癌

THERAPY-INDUCED ACUTE LEUKEMIA ( REPORT OF 1 CASE )
Xu Shirong Jia Wenjua. THERAPY-INDUCED ACUTE LEUKEMIA ( REPORT OF 1 CASE )[J]. Journal of Hebei Medical University, 1988, 0(1)
Authors:Xu Shirong Jia Wenjua
Affiliation:Xu Shirong Jia Wenjua Department of Internal Medicine,Second Affiliated Hospital
Abstract:A case of breast carcinoma treated with cytotoxic drug ( thiotepa ) developing secondary myelodysplaslic syndrome ( MDS ) and terminating in acute monocytic leukemia ( AMOL ) was reported. The interval from the initiation of cytotoxic drug to the development of stcondary MDS was 7 years. By two years after MDS it terminated in AMOL. The problem involving MDS and leukemia transformation indued by cytotoxic drugs was briefly discussed.
Keywords:cytotoxic drug  leukemia  myelodysplastic syndrome(MDS)  breast carcinoma
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