微创手术治疗脊柱转移瘤的临床研究 |
| |
引用本文: | 张忠民,张超,韩秀鑫,马育林,张岩,刘永恒,卢凤,赵成亮,王国文.微创手术治疗脊柱转移瘤的临床研究[J].中国肿瘤临床,2022,49(13):682-687. |
| |
作者姓名: | 张忠民 张超 韩秀鑫 马育林 张岩 刘永恒 卢凤 赵成亮 王国文 |
| |
作者单位: | 1.天津医科大学肿瘤医院骨与软组织肿瘤科,国家肿瘤临床医学研究中心,天津市"肿瘤防治"重点实验室,天津市恶性肿瘤临床医学研究中心(天津市300060) |
| |
摘 要: | 目的 探索经皮椎弓根螺钉联合微创治疗手段在脊柱转移瘤中的疗效。 方法 回顾性分析2019年10月至2021年9月天津医科大学肿瘤医院收治的脊柱转移瘤患者15例。患者均行经皮椎弓根螺钉联合微创治疗,术后给予综合治疗,治疗前和治疗后3个月对患者疼痛、神经损伤、功能状态等进行评估。 结果 患者随访3~23个月,平均生存时间为13.5个月,中位生存时间14.0个月。平均手术时间为(232.3±17.9)min,术中出血量为(393.3±64.9)mL,椎体骨水泥平均注射量3.38 mL。治疗前VAS评分(7.67±0.25)分,术后3个月VAS评分(2.73±0.15)分,治疗后疼痛明显缓解(P<0.01);14例患者Frankel分级提高1个等级,1例患者术前为Frankel D级,经过微创手术治疗后分级无变化;术前、术后3个月KPS评分得到明显改善(P<0.01)。 结论 经皮椎弓根螺钉联合小切口椎板减压手术能够有效缓解脊髓压迫症状,减轻疼痛,提高患者生存质量。
|
关 键 词: | 经皮椎弓根螺钉固定术 小切口 椎体成形 脊柱转移瘤 |
收稿时间: | 2021-11-15 |
Clinical study of minimally invasive surgery for spinal metastases |
| |
Institution: | 1.Department of Bone and Soft Tissue Sarcoma , Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin’s Clinical Research Center for Cancer, Tianjin 300060, China2.Department of Spinal Surgery, The Affiliated Hospital of Qingdao University, Qingdao 266071, China |
| |
Abstract: | Objective To assess the efficacy of percutaneous pedicle screw fixation combined with minimally invasive surgery for spinal metastases. Methods From October 2019 to September 2021, fifteen patients with spinal metastases from Tianjin Medical University Cancer Institute & Hospital were retrospectively analyzed. The patients underwent percutaneous pedicle screw internal fixation combined with minimally invasive surgery. The patients also received comprehensive treatments after surgery. They were followed up after treatment, and pain, nerve injury, and functional status were evaluated before and three months after surgery. Results The patients were followed up for 3-23 months. The average and median survival times of the patients were 13.5 and 14.0 months, respectively. The average operation duration was (232.3±17.9) min, amount of intraoperative bleeding was (393.3±64.9) mL, and average amount of vertebral bone cement injection was 3.38 mL. The visual analogue scale(VAS) scores were 7.67±0.25 and 2.73±0.15 before and three months after surgery, respectively. Pain was significantly relieved after surgery (P<0.01); the Frankel grade increased by one grade in 14 patients. One patient had Frankel grade D before surgery, and there was no change in the grade after surgery. The Karnofsky performance scale score significantly improved before and 3 months after surgery (P<0.01). Conclusions Percutaneous pedicle screw fixation combined with short incision can effectively alleviate symptoms of spinal cord compression, reduce pain, and improve patients’ quality of life. |
| |
Keywords: | |
|
| 点击此处可从《中国肿瘤临床》浏览原始摘要信息 |
| 点击此处可从《中国肿瘤临床》下载免费的PDF全文 |
|