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Safety and efficacy of ampreloxetine in symptomatic neurogenic orthostatic hypotension: a phase 2 trial |
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| Authors: | Kaufmann Horacio Vickery Ross Wang Whedy Kanodia Jitendra Shibao Cyndya A Norcliffe-Kaufmann Lucy Haumann Brett Biaggioni Italo |
| Institution: | 1.Department of Neurology, Dysautonomia Center, NYU Langone Health, New York University School of Medicine, 530 First Avenue, Suite 9Q, New York, NY, 10016, USA ;2.Theravance Biopharma Ireland Limited, Dublin, Ireland ;3.Formerly of Theravance Biopharma US, Inc., South San Francisco, CA, USA ;4.Theravance Biopharma US, Inc., South San Francisco, CA, USA ;5.Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA ;6.Formerly of Theravance Biopharma UK Limited, London, UK ; |
| Abstract: | Clinical Autonomic Research - In neurogenic orthostatic hypotension, blood pressure falls when upright owing to impaired release of norepinephrine, leading to dizziness. Ampreloxetine, a selective... |
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