Concomitant Choroidal Melanoma and Non-Hodgkin Lymphoma in Two Adult Patients: Case Report

Objective

To report two cases of concomitant choroidal melanoma and intraocular non-Hodgkin lymphoma in two patients.

Design

Case report.

Participants

Two patients with yellow creamy infiltrates in fundo.

Intervention

Both patients had a complete ophthalmologic evaluation and histology was obtained after enucleation of the affected eye.

Main Outcome Measures

Histology findings of the enucleated eyes.

Results

One patient showed a choroidal melanoma with a primary non-Hodgkin lymphoma located solely in the affected eye. The other patient showed a systemic non-Hodgkin lymphoma with ocular manifestations concomitant with a choroidal melanoma.

Conclusions

In the presence of yellow creamy infiltrates one should include a choroidal lymphoma in the differential diagnosis even if there is another clear pathologic condition. Furthermore in those cases systemic disease should be excluded.Key Words: Non-Hodgkin lymphoma, Uveal melanoma, Choroidal melanoma