| 3D打印复合PVA骨组织工程支架研究现状 |
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| 作者姓名： | 刘小元 张凯 韩祥祯 左新慧 李君 何惠宇 |
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| 作者单位： | 新疆医科大学第一附属医院（附属口腔医院）口腔修复科·新疆维吾尔自治区口腔医学研究所 |
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| 基金项目： | 国家自然科学基金项目(81660177);自治区科技支疆项目计划(2018E02060) |
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| 摘 要： | 3D打印复合多孔性骨组织工程支架已成为研究热点。复合聚乙烯醇(polyvinyl alcohol,PVA)具备良好生物相容性及可降解性能,但因不能抵抗较大机械抗力,不能单独制备支架,复合其他机械性能佳及生物相容性良好的材料,可表现出良好的生物相容性、可降解性及机械性能等优点,因此3D打印复合PVA支架材料可以优化PVA支架的性能,本文从3D打印骨组织工程支架技术、PVA、复合PVA支架在体内外骨形成效果等方面作一综述。
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| 关 键 词： | 骨缺损 3D打印 光固化成型 选择性激光烧结 熔融层积成型 喷墨印刷 生物墨水 组织工程骨支架 聚乙烯醇 骨形成 |
Research status of 3D-printed composite PVA bone tissue engineering scaffolds |
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| Authors: | LIU Xiaoyuan ZHANG Kai HAN Xiangzhen ZUO Xinhui LI Jun HE Huiyu |
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| Institution: | (Xinjiang Uygur Autonomous Region Institute of Stomatology,De?partment of Prosthodontics,the First Affiliated Hospital(Affiliated Stomatological Hospital)of Xinjiang Medical Uni?versity,Urumqi 830054,China) |
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| Abstract: | Three dimensionally printed composite porous bone tissue engineering scaffolds have become a research focus.Composite polyvinyl alcohol(PVA) has good biocompatibilityand degradability,but it cannot be prepared independently because it cannot resist highmechanical resistance.This material shows many advantages,such as good biocompatibility,degradability and mechanical properties,when compounded with other materials with good mechanical properties and good biocompatibility.Therefore,3 D printed composite PVA scaffold material can optimize the performance of PVA scaffolds.This article reviews 3 D printing bone scaffold technology,polyvinyl alcohol(PVA),and composite PVA scaffolds for in vivo and in vitro bone formation. |
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| Keywords: | bone defect 3D printing stereo lithography appearance selective laser sintering fused deposi?tion modeling ink jet printing bioink tissue engineering bone scaffold polyvinyl alcohol bone formation |
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