A new internal pair production branching ratio of 90Y: the development of a non-destructive assay for 90Y and 90Sr. |
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Authors: | R G Selwyn R J Nickles B R Thomadsen L A DeWerd J A Micka |
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Affiliation: | Department of Medical Physics, University of Wisconsin-Madison, Madison, WI 57306, USA. selwyn@wisc.edu |
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Abstract: | (90)Y is utilized as a therapeutic radioisotope in radiolabeled monoclonal antibodies and in microspheres for targeted radiation therapy of the liver. Currently, the widely used dose calibrator assay of (90)Y can have uncertainties exceeding +/-10%. A non-destructive assay using spectroscopy is possible by reducing the currently published uncertainty (+/-12%) in the internal pair production branching ratio for the 0(+)-0(+) transition of (90)Zr. A high-purity germanium detector was used to determine the branching ratio to be (31.86+/-0.47) x 10(-6). |
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