繁木泻土汤治疗高脂血症的临床研究

目的:探讨自拟繁木泻土汤治疗高脂血症的临床疗效。方法:150例高脂血症患者随机分为治疗组和对照组各75例。治疗组采用繁木泻土汤,1剂/d;对照组采用阿托伐他汀,20 mg,1次/d。疗程8周。观察两组血脂、血液流变指标。结果:治疗组总有效率81.3%,对照组为73.3%;两组治疗后血脂及载脂蛋白各指标较治疗前明显改善(P<0.05,P<0.01);治疗组除TC外,各指标改善均优于对照组(P<0.05,P<0.01);治疗后治疗组血液流变学各项指标均较治疗前显著降低,且均优于对照组(P<0.01)。结论:繁木泻土汤能有效调节高脂血症的血脂,改善患者血流状态,对高脂血症患者安全有效。

Clinical research on Fanmu Xietu Tang for Treating Hyperlipemia

Objective: To study the clinical curative effect of Fanmu Xietu Tang (FXT) for treating hyperlipemia. Method: One hundred and fifty patients with hyperlipidemia were randomly divided into treatment group and control group (n=75 each).The treatment group was given FXT, 1 agent daily.The control group was given atorvastatin, 20 mg daily.Treatment was lasted for 8 weeks.Blood lipids, blood rheological indexes were investigated. Result: Total effective rate in treatment group was 81.3%, and that was 71.3% in the controls.After treatment, blood lipids and apolipoprotein in two groups were obviously improved compared with those before treatment (P<0.05, P<0.01).Except total cholesterol, other indexes in the treatment group were better than those in the controls (P<0.05, P<0.01).After treatment the hemorheological indexes in the treatment group were improved compared with those before treatment, and better than those in control group (P<0.01). Conclusion: FXC could effectively control blood lipids in hyperlipidemia and improve blood flow condition.It is safe and effective.