济南市36例职业性哮喘患者哮喘控制测试与肺功能检测

目的]探讨哮喘控制测试(ACT)与肺功能检测在职业性哮喘管理中的应用价值。方法]对36例职业性哮喘患者急性发作期和缓解期进行ACT评分、记录肺功能指标的最大呼气流速峰值(PEF)、用力呼气25%肺活量时流速(PEF25)、用力呼气50%肺活量时流速(PEF50)、用力呼气75%肺活量时流速(PEF75)。结果]调查哮喘患者36例,急性发作期ACT测试评分<10、10～19、>20分者分别为41.67%、58.33%、0.00%;缓解期分别为0、10.34%、89.66%。哮喘发作期,PEF与PEF25、PEF50、PEF75中度异常率、重度异常率差异均有统计学意义(P<0.01);哮喘缓解期,PEF与PEF25、PEF50、PEF75轻度异常者检测值、中度异常率差异均有统计学意义(P<0.01或0.05)。结论]ACT测试简便易行,可作为门诊筛查职业性哮喘是否控制的检测手段,肺功能检测中的小气道指标是评估哮喘控制程度、指导正确用药的主要依据。

Asthma Control Test and Pulmonary Function Detection Among 36 Cases of Professional Asthma Jinan City

Objective]To study the value of clinical application of Asthma Control Test(ACT) and pulmonary function test(PFT) in patients with occupational asthma.Methods]Totally 36 asthmatic patients at the acute episode and remission stage were given ACT score and PET including peak expiratory flow(PEF),maximal peak expiratory flow at 25%,50%,75% of vital capacity(PEF25,PEF50,PEF75).Results]The percentages of occupational asthmatic patients whose ACT scores<10,10-19,>20 were 41.67%,58.33% and 0.00% respectively at the acute episode stage,and 0.00%,10.34% and 89.66% respectively at the remission episode stage.All indexes of PFT were abnormal at the acute episode,and compared with the PEF,the severities of PEF25,PEF50,PEF75 were higher than that of PEF in moderate and severe degree(P<0.01).At remission stage,all indexes of severe abnormalities were all remittent,but the abnormalities of were still higher than that of PEF in mild and moderate degree(P<0.01 or <0.05).Conclusion]ACT is easy and practical,it may serve in clinic as a means to screen whether occupational asthma is controlled or not,the indexes of small airway in PFT are the main basis to assess the controlling degree of asthma and guide medication.