| Abstract: | The quality of soyasaponin (Ts) from soyabean leaves was similar to that from soyabean. The depressor and bradycardia effects of Ts,injected through peripheral pathway (i. v) wereobtained,and a dose-effect relationship was demonstrated. The depressor effect was not antagonizedby atropine,and could not weaken the pressor action induced by the administration of noradrenaline.It showed that thi8 depressor effect neither was induced by the excitation of M receptors nor was induced by blocking the a receptors, and it was perhaps realized through other receptors or by the directddstory action of Ts on arteries. While the animal blood pressure was in lower level, Ts could raisethe left ventricle systolic pressure (LVSP), the maximum change rate of ventricle pressure (+dp/dtmax), systolic arterial pressure (SAP) and diastolic arterial pressure (DAP). Mean arterial pressure(MAP) could be decreased by phentolamine and proprenolol. |
