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含5%硝酸钾牙膏抗牙本质敏感的临床研究
引用本文:庄文捷,曹东. 含5%硝酸钾牙膏抗牙本质敏感的临床研究[J]. 上海口腔医学, 2011, 20(6): 638-640
作者姓名:庄文捷  曹东
作者单位:1. 泉州医学高等专科学校附属人民医院口腔科,福建泉州,362000
2. 上海交通大学医学院附属第九人民医院·口腔医学院牙体牙髓病科,上海市口腔医学重点实验室,上海200011
基金项目:上海市科学技术委员会资助项目(08DZ2271100); 上海市重点学科建设项目(S30206)
摘    要:目的:评价含5%硝酸钾牙膏减轻牙本质敏感症状的临床效果。方法:根据随机、双盲、平行设计的试验原则,将63名受试者随机分为试验组(含5%硝酸钾牙膏)和对照组(普通牙膏)进行试验,试验周期为4周。采用视觉模拟疼痛评分法(VAS)分别记录基线和4周后受试牙的牙敏感指数。采用SPSS13.0软件包对数据进行非参数检验。结果:使用牙膏4周后,试验组牙本质敏感VAS值显著低于基线(P<0.05)。与对照组相比,试验组使用牙膏前后牙本质敏感VAS记分之差显著高于对照组(P<0.05)。结论:含5%硝酸钾牙膏具有显著的抗牙本质敏感效果,可改善患者的整体舒适度。

关 键 词:临床试验  牙过敏  硝酸钾  牙膏

Efficacy of a dentifrice containing 5% potassium nitrate on dental hypersensitivity
ZHUANG Wen-jie , CAO Dong. Efficacy of a dentifrice containing 5% potassium nitrate on dental hypersensitivity[J]. Shanghai journal of stomatology, 2011, 20(6): 638-640
Authors:ZHUANG Wen-jie    CAO Dong
Affiliation:ZHUANG Wen-jie1,CAO Dong2.(1.Department of dentistry,People's Hospital Affiliated to Quanzhou Medical College.Quanzhou 362000,Fujian Province,2.Department of Endodontics,Ninth People's Hospital,College of Stomatology,Shanghai Jiao Tong University School of Medicine,Shanghai Key Laboratory of Stomatology.Shanghai 200011,China)
Abstract:PURPOSE:To evaluate the efficacy of a dentifrice containing 5% potassium nitrate(test) on dental hypersensitivity compared with the fluoride dentifrice(control) over a 4-week period.METHODS: The study design was a randomized,double-blinded,controlled clinical trial.63 subjects were randomly divided into 2 groups,with 31 were given a 5% potassium nitrate dentifrice(experimental group) and the other 32 given a fluoride dentifrice(control group).Both groups were instructed to brush their teeth twice a day.An a...
Keywords:Clinical trial  Dental hypersensitivity  Potassium nitrate  Dentifrice  
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