老年性骨量减少的证候特征及其与骨密度的相关性研究

目的 探讨老年性骨量减少的证候特征及其与骨密度的相关性.方法 对91名老年性骨量减少患者进行中医证候评定,39例骨密度正常老年人作为对照组(正常组),Pearson相关分析等统计学方法用于统计学分析.结果 老年性骨量减少最常出现的中医证候是肾精亏虚证、痰浊内阻证、气虚证和血瘀阻络证,与正常组相比,在肾精亏虚证和痰浊内阻证具有显著性差异;与骨密度(BUA)相关的有肾精亏虚证,与超声传导速度(SOS)相关的有肾精亏虚证和痰浊内阻证,两者呈负性相关,即肾精亏虚证和痰浊内阻证积分越高,发生老年性骨量减少的危险性越大.结论 骨密度与肾精亏虚证和痰浊内阻证具有密切关系,从而验证了它们在老年性骨量减少中的客观存在.

Correlation between syndrome characteristics of senile bone loss and bone mineral density

Objective To investigate the correlation between syndrome characteristics of senile bone loss and bone mineral density (BMD). Method The Chinese medical syndromes were evaluated in 91 patients with senile bone loss, and other 39 normal old men were chosen as the control group. The statistical methods, such as Pearson correlation analysis, were used to analyse the data. Result The most common Chinese medical syndromes in senile bone loss were the syndrome of deficiency of kidney essence, syndrome of phlegm obstruction, syndrome of qi insufficiency and syndrome of collateral obstructed by blood stasis. There was significant differencse in the syndrome of deficiency of kidney essence and syndrome of phlegm obstruction compared with the control group, and the syndrome of deficiency of kidney essence was correlated to BMD. The syndrome of deficiency of kidney essence and syndrome of phlegm obstruction had negative relations to the speed of sound (SOS) in ultrasonic, which meant the risk of senile bone loss would be greater when the integrals of the syndrome of deficiency of kidney essence and syndrome of phlegm obstruction were increasing. Conclusion BMD was correlated to the syndrome of deficiency of kidney essence and syndrome of phlegm obstruction, which proved these two syndromes could be seen objectively in senile bone loss.