颅内原发性恶性淋巴瘤临床和影像学分析

目的为了提高对颅内原发性恶性淋巴瘤的认识.方法收集经手术、病理和免疫组化证实,资料齐全的颅内恶性非霍杰金淋巴瘤21例,回顾性分析其临床、CT和MR表现.结果21例临床表现均不一样,病程短.CT和MRI上有一定的特点：可发生颅内任何部位,肿块在CT上表现为均匀等或稍高密度,邻近病灶的脑组织轻、中度水肿,MRI上以等信号为主,增强扫描后均显著强化.肿瘤多为分叶状,边界模糊,常沿软脑膜蔓延.结论虽然颅内恶性淋巴瘤临床表现多种多样,但其CT和MRI表现具有一定的特点,对其术前诊断具有重要意义.

Analysis of Clinical and Image manifestations in Patients with Primary Intracranial Non-Hodgkin Lymphoma

Objective To enhance the understanding of primary intracranial malignant lymphoma. Method The clinical manifestations and findings of CT and MRI were analyzed retrospectively in 21 patients with primary intracranial malignant non-Hodgkin lymphoma proved by surgery, pathology and immunohistochemistry. Results The clinical manifestation varied in 21 patients with primary intracranial malignant non-Hodgkin lymphoma, who had short disease course. The tumors were homogeneous isodensity or slightly-higher density on CT. The mild-moderate edema in the cerebral tissue adjacent to the lesions was observed on CT. The MRI signal intensity of the tumor was mainly homogeneous and markedly enhanced after contrast administration. Lymphoma with indefinite borders was foliiform, and extended along the pia mater. Conclusion Though the clinical manifestation of intracranial malignant lymphoma is various, the CT and MRI can play an important part in its diagnosis because of their characteristics.