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负压对创面血流量的影响
引用本文:许龙顺,陈绍宗,乔骋,李学拥. 负压对创面血流量的影响[J]. 医学争鸣, 2000, 21(8): 976-978
作者姓名:许龙顺  陈绍宗  乔骋  李学拥
作者单位:第四军医大学唐都医院整形科,陕西,西安,710038
摘    要:目的:研究负压对创面局部血流量的影响,方法采用猪的新鲜和肉芽创面模型,以特制的闭事敷料封闭创面,负压装置调控创面微环境负压,用激光多普勒血流仪连续测定负压前后两种创面血流量的动态变化。结果新鲜创面:8kPa负压时创面血流量即明显升高;16kPa负压时其峰值接近基线血流量的4倍,持负压30min后维持在基线水平的2倍左右左右;20kPa负压以上时血流量增加后很快降至基线水平;16kPa间歇性负压时血

关 键 词:创面愈合 血流量 负压
修稿时间::

Effects of negative pressure on wound blood flow
XU Long-Shun,CHEN Shao-Zong,QIAO Cheng,LI Xue-Yong. Effects of negative pressure on wound blood flow[J]. Negative, 2000, 21(8): 976-978
Authors:XU Long-Shun  CHEN Shao-Zong  QIAO Cheng  LI Xue-Yong
Abstract:AIM To study the effect of negative pressure on local wound blood flow. METHODS A pig acute and granulation wound model was established. A special occlusive dressing was applied to seal the wound, and negative pressure was applied and transmitted to the wound in a controlled manner. Blood flow was recorded continuously before and after the application of negative pressure on Laser Doppler flowmeter. RESULTS In the acute wound, blood flow increased when the negative pressure was at the level of 8 kPa. The peak blood flow recorded at 16 kPa negative pressure was up to 4 times the baseline blood flow. Blood flow remained around 2 times the baseline values after 30 minutes ofcontinuous application of negative pressure. The increase declined and reached the baseline soon after the application of negative pressure at the level of 18 kPa and above. Intermittent application of negative pressure resulted in blood flow that fit a square wave pattern. In the granulation wound, the peak blood flow recorded at 16 kPa negative pressure was about 4 times the baseline values. However, the increases didn't decline significantly after 15 minutes of continuous application of negative pressure. CONCLUSION It can be concluded that negative pressure can increase blood flow significantly.
Keywords:wound healing  blood flow  negative pressure
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