Gd-EOB-DTPA对Gd-DTPA延迟期等高信号小肝癌的诊断价值

目的：探讨肝脏特异性对比剂Gd—EOB-DTPA对Gd—DTPA延迟期呈等或高信号小肝癌的诊断价值。方法：回顾性分析33例肝硬化小肝癌患者（41例病灶）在Gd-DTPA及Gd—EOB-DTPA常规平扫及动态增强各期的表现，重点观察病灶在Gd—EOB-DTPA肝胆期的表现。结果：41个小肝癌病灶中7个于Gd—DTPA延迟期呈等或高信号，其中6个在Gd-E0昏DTPA增强扫描肝胆期表现为低信号，1个表现为稍高信号；其余34个小肝癌病灶在Gd-DTPA和Gd—EOB-DTPA增强扫描中均表现为“速升速降”型强化方式。结论：Gd—EOB-DTPA动态增强联合肝胆期扫描能够为在Gd—DT—PA延迟期呈等或高信号小肝癌的定性诊断提供更多信息，提高不典型小肝癌的栓出率。

Value of Gd-EOB-DTPA hepatobiliary phase for diagnosis of small hepatocellular carcinoma with iso/hyper-intensity in delayed phase of Gd-DTPA

Objective：To investigate the value of Gd-EOB-DTPA hepatobiliary phase for diagnosis of small hepatocel- lular carcinoma （SHCC） with iso/hyper-intensity in delayed phase of Gd-DTPA. Methods： A total of 33 cirrhotic patients with 41 confirmed SHCC were analyzed retrospectively. The manifestations of lesions on conventional native phase and dy- namic contrast enhancement of both Gd-DTPA and Gd-EOB-DTPA were observed, especially on hepatobiliary phase of Gd- EOB-DTPA. Results：Of the 41 SHCC,7 lesions showed iso/hyper-intensity in delayed phase of Gd-DTPA,including 6 le- sions showing hypo-intensity in hepatobiliary phase of Gd-EOB-DTPA and one showing slight hyper-intensity. The rest 34 lesions showed ＂rapid enhancing and rapid washout＂ in dynamic contrast enhancement with Gd-DTPA and Gd-EOB-DTPA. Conelusion..Gd-EOB-DTPA dynamic contrast enhancement in combination with hepatobiliary phase can provide more information in the diagnosis of SHCC which showed iso/hyper-intensity in delayed phase of Gd-DTPA,and thus may improve the diagnostic accuracy of atypical SHCC.