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乌头碱中毒致心律失常60例临床研究
引用本文:张阳,沈丽娟,殷兆芳,王长谦.乌头碱中毒致心律失常60例临床研究[J].中国医药导刊,2012,14(2):201+203.
作者姓名:张阳  沈丽娟  殷兆芳  王长谦
作者单位:上海交通大学医学院附属第九人民医院心内科;云南省祥云县人民医院内一科
摘    要:目的:探讨急性乌头碱中毒致心律失常患者的临床特征及抢救办法。方法:分析60例急性乌头碱中毒致心律失常患者的临床资料。结果:60例患者心电图表现缓慢性心律失常24例,快速性心律失常36例(含致命性心律失常2例),经应用阿托品、盐酸戊乙奎醚等治疗后,全部好转或治愈出院。结论:乌头碱中毒通常会引起心律失常,有时可出现致命性严重的心律失常。早期及时使用抗胆碱能药物如阿托品、盐酸戊乙奎醚,必要时使用利多卡因等治疗可提高抢救成功率。

关 键 词:乌头碱中毒  心律失常  抗胆碱能药物

The Study of 60 Patients with Arrythmia due to Acute Aconites Alkali Poisoning
Institution:Zhang Yang 1,Shen Li-juan 2,Yin Zhao-fang 1,et al.(1 The Department of Cardiology of the Ninth HospitalAffiliated to Medical College of Shanghai Jiaotong University,Shanghai 200011,China;2 The Department of No.1 Intermedichine of Xiangyun county hospital of Yunnan Province,Xiangyun 672100,China)
Abstract:Objective:To explore the clinical characteristic and rescue measures of the patients with arrythmia due to acute aconites alkali poisoning。 Methods:An analysis of the clinical data of 60 patients with arrythmia due to acute aconites alkali poisoning was done.Result:The ECG of 60 patient shows:bradycardia 24 cases,tachicardia 36 cases,including lethal arrythmia 2cases.All patients were discharged from the hospital with disease being relieved or cured after treatment by atropine,penehyclidine hydrochloride,etc.Conclusion:Aucte aconites alkali poisoning may cause arrhythmias in common,and sometimes it can be deadly serious arrhythmias.Using anti-cholinergic drugs such as atropine,penehyclidine hydrochloride in time,accompany with lidocaine when necessary can improve the success rate of rescuing measures.
Keywords:Aconites alkali poisoning  Arrythmia  Anti-cholinergic drugs
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