Vasoactive intestinal polypeptide (VIP)-containing neurons in the spinal cord of the rat and their projections |
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| Authors: | K Fuji E Senba Y Ueda M Tohyama |
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| Affiliation: | 1. Department of Anesthesiology, Osaka Dental University, 1-47 Kyobashi, Higashiku, Osaka (540) Japan;2. Department of Neuroanatomy, Institute of Higher Nervous Activity, Osaka University Medical School, 4-3-57 Nakanoshima, Kitaku, Osaka (530) Japan |
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| Abstract: | The distribution of vasoactive intestinal polypeptide (VIP)-like immunoreactive structures in the rat spinal cord and their projections were investigated by means of an immunofluorescent method. In the normal rat, a small number of VIP-positive fibers were observed in the superficial layer of the dorsal horn and in the lateral funiculus. With colchicine pretreatment, VIP-positive neurons were demonstrated in the lateral spinal nucleus (lsn) and in the lamina X (Rexed). Transections of the spinal cord at various levels revealed that some of the VIP neurons in the lsn might project to supraspinal areas via lateral funiculus. |
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| Keywords: | vasoactive intestinal polypeptide immunohistochemistry spinal cord lateral spinal nucleus rat |
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