小儿病毒性脑炎的临床观察

目的研究病毒性脑炎患儿多器官功能损害的发生情况。方法检测99例住院病毒性脑炎患儿的血糖、电解质、肝肾功能、心肌酶谱、高敏C反应蛋白（hs—CRP）及胱抑素c。结果99例患儿中低钙血症28例（28．9％），高磷血症38例（39．2％），高血糖17例（27．9％）；AⅡ异常3例，AST异常18例；肌酸激酶同工酶（CK—MB）异常27例（27．3％）；胱抑素C升高5例，其中年龄〈8个月3例（1．23～1．47mg／L）、〉3岁2例（1．68和2．31mg／L）。hs—CRP〉40mg/L仅1例，但伴有肺炎。75例同时检测CK—MB和hs—CRP，2项同时升高11例，其中1项以上异常者68例。结论病毒性脑炎患儿存在心肌损伤、应激性高血糖、电解质紊乱等多器官功能的损害，及早予以检测及治疗，有利于改善患儿预后。

Clinical observation of viral encephalitis in children

Objective To investigate the occurrence condition of multiple organ injuries in children with viral encephalitis. Methods The blood glucose, electrolyte, hepatic and renal function, myocardial enzymes, high-sensitlvity C reactive protein （hs-CRP）and cystatin C of 99 hospitalized children with viral encephalitis were detected. Results Among these patients, hypocalcemia was 28 cases（28.9% ） , hyperphosphatemia was 38 cases （ 39.2% ） , hyperglycemia was 17 cases （ 27.9% ） ; alanine aminotransferase （ ALT ） in 3 cases and aspartate aminotransferase （AST） in 18 cases were abnormal; Creatine kinase isoenzyme （CK-MB） in 27 cases was abnormal （27.3%） ; the level of cystatin C elevated in 5 cases. Only l case had pneumonia hs-CRP）40 mg/L. CK-MB and hs-CRP were measured at the same time in 75 cases and all elevated was 11 cases, and 68 eases among them had one or two abnormal levels. Conclusions Children with viral encephalitis may have multiple organ injuries such as myocardial injury, stress hyperglycemia and electrolyte disorder. It is beneficial to improve the children＇s prognosis if they are treated as early as possible.