重楼属植物的药用价值及其化学物质基础

该文综述了延龄草科重楼属植物的传统利用及其化学物质基础。重楼属包括40个种及变种,作为药用植物使用的有18个,这些药用植物在传统利用上有相似性。目前已对14个种及变种重楼的化学成分进行了研究,报道了207个化合物,其中甾体皂苷121个。甾体皂苷是重楼属植物的主要活性成分,很好地解释了其在治疗癌症、疔、疮、出血、胃炎等疾病上的利用。由于它们在药用功能、化学成分等方面的相似性,重楼属植物在资源相互替代上具有可行性。在重楼属化学成分、药理活性、生物学特性、毒理学等方面,还值得深入研究。

Medicinal values and their chemical bases of Paris

Medicinal values and their chemical bases of Paris (Trilliaceae) are reviewed. Paris plants include 40 species and varieties. Among them, 18 ones are medicinal plants with similarity in traditional uses. Fourteen species have been studied phytochemically, which led to isolation of 207 compounds including 121 steroidal saponins. These saponins are major active constituents from Paris plants, which can explain the traditional uses of the plants to treat cancer, malignant boil, bleeding, gastritis, and so on. The similarity in medicinal uses and chemical constituents of Paris plants implies the possibility of resource substitution among these species. It is worth to further investigate Paris plants in chemical constituents, pharmacological activity, biological property, and toxicology.