| 泪腺多形性腺瘤表皮生长因子受体表达的研究 |
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| 引用本文： | 郑磊,范忠义.泪腺多形性腺瘤表皮生长因子受体表达的研究[J].中华眼科杂志,1995,31(3):212-213. |
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| 作者姓名： | 郑磊 范忠义 |
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| 作者单位： | 解放军第二军医大学第一附属医院眼科，解放军沈阳军区总医院眼科 |
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| 摘 要： | 应用免疫组化的方法观察３２例泪腺多形性腺瘤表皮生长因子受体的表达，结果１０例染色阳性，而正常泪腺组织染色阴性，阳性染色限于索条样、腺管排列及鳞状化生的肿瘤细胞，实验结果提示泪腺多形性腺瘤表皮生长因子受体的表达水平明显高于正常泪腺组织，表皮生长因子受体可能主要表达于导管起源的肿瘤细胞。
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| 关 键 词： | 腺瘤 表皮生长因子 受体 泪器肿瘤 病理学 |
A Study on expression of epidermal growth factor receptor in pleomorphic adenoma of lacrimal gland |
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| Zheng Lei,Fan Zhongyi,He Shufang,et al.A Study on expression of epidermal growth factor receptor in pleomorphic adenoma of lacrimal gland[J].Chinese Journal of Ophthalmology,1995,31(3):212-213. |
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| Authors: | Zheng Lei Fan Zhongyi He Shufang |
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| Abstract: | Expression of epidermal growth factor(EGF)receptor was examined in 32 cases of pleo-morphic adenoma of lacrimal gland by means of an immunohistochemical method.While normal lacrimal glands were all negative for the antigen,EGF receptor was positive in 10 pleomorphic adenomas and the positive staining was mainly limited in the tumor cells in trabecular or duct-like arrangement or squa-mous metaplastic epithelium,These data suggest that the expression of EGF receptor be significantly higher in pleomorphic adenoma than in normal lacrimal gland,and also suggest that EGF receptor be ex-pressed in the neoplastic cells which are considered to be of duct origin. |
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| Keywords: | Lacrimal apparatus diseaseses Adenoma Epidermal growth facor Receptor |
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