湖南邵阳地区汉族人群骨质疏松症的中医证候特征研究

目的:探讨湖南邵阳地区汉族人群骨质疏松症的中医证候特征。方法:按事先确定的病例选择标准选择患者,对其进行辨证分析,所得结果采用统计软件进行频次分析和聚类分析。结果:①464例患者共有83种症状和异常舌脉,其中腰背酸软、腰背酸痛、肢酸软痛、腰背冷、疲乏少力、动作迟缓、反应迟钝、齿松、健忘、目干涩、面色萎黄、舌质淡红、舌质暗红、舌有瘀斑、舌苔薄白、舌苔少、脉细弱、脉弦、脉细涩聚为1类,其余为2类。②对各复合证候进行聚类分析:阳虚血瘀、阳虚寒凝、阴虚髓亏、阴虚血瘀、阳气滞血瘀、气虚血瘀聚为1类,其余为2类。③男性患者较早出现湿阻、寒湿、阳虚证,女性患者较早出现气滞与阴虚证。④对脏腑定位进行聚类分析,肾、肝肾、脾肾为1类,其余为2类。⑤主要证候出现频次依次是:肝肾(包括心)阴虚血瘀105例、阴虚髓亏81例,肾(包括脾、肺、肝、心)阳虚髓亏73例、气虚血瘀73例、阳虚血瘀51例,痰湿瘀阻27例,气滞血瘀54例。结论:湖南邵阳地区汉族人群原发性骨质疏松症的中医证候以虚、瘀为主,病位主要是肾、肝、脾。

Study on the characteristics of traditional Chinese medicine symptom complex of osteoporosis in the Han people in Shaoyang region of Hunan province

Objective：To study the characteristics of traditional Chinese medicine（TCM）symptom complex of osteoporosis in the Han people in Shaoyang region of Hunan province.Methods：Patients met the predetermined selection criteria were processed with dialectical analysis,and their results were studied from frequency analysis and cluster analysis by using statistical software.Results：①464 cases showed 83 kinds of symptoms and abnormal signs of tongue and pulse.Some of the previously mentioned symptoms and signs were classified as class 1,while the others were classified as class 2.The symptoms and signs of class 1 included lassitude,ache and cold in lumbus and back,ache and weakness in limbs,fatigue,bradykinesia,slow response,loose teeth,amnesia,xerophthalmia,sallow complexion,pale or dark red of the tongue body,ecchymosis on tongue,white or thin tongue coating,thin pulse,wiry pulse and rough pulse.②Cluster analysis was performed on every composite symptom complex.The following symptom complex as yang deficiency and blood stasis（阳虚血瘀）,yang deficiency with exuberant cold（阳虚寒凝）,yin deficiency with marrow depletion（阴虚髓亏）,yin deficiency and blood stasis（阴虚血瘀）,qi stagnation and blood stasis（气滞血瘀）,qi deficiency and blood stasis（气虚血瘀）were classified as class 1;while the others were classified as class 2.③The symptom complex of damp obstruction（湿阻）,cold-damp（寒湿）and yang deficiency（阳虚）appeared earlier in male patients;while the symptom complex of qi stagnation（气滞）and yin deficiency（阴虚）appeared earlier in female patients.④Cluster analysis was performed on entrails orientation.Kidney,liver-kidney and spleen-kidney were classified as class 1;while the others were classified as class 2.⑤Frequency of occurrence for the main symptom complex were listed in order as follows：yin deficiency and blood stasis（阴虚血瘀）and yin deficiency with marrow depletion（阴虚髓亏）in liver-kidney（including heart）were found in 105 cases and 81 cases respectively;yang deficiency with marrow depletion（阳虚髓亏）,qi deficiency and blood stasis（气虚血瘀）and yang deficiency and blood stasis（阳虚血瘀）in kidney（including spleen,lung,liver and heart）were found in 73 cases,73 cases and 51 cases respectively;phlegm-damp obstruction（痰湿瘀阻）was found in 27 cases;qi stagnation and blood stasis（气滞血瘀）was found in 54 cases.Conclusion：For the Han people in Shaoyang region of Hunan province,the main TCM symptom complex of primary osteoporosis are deficiency and stasis,and the main location of disease are kidney,liver and spleen.