病毒性脑炎患者血清肌酸激酶脑型同工酶的动态变化

目的观察急性病毒性脑炎血清肌酸激酶脑型同工酶（CK—BB）的动态变化。方法取健康献血员（健康对照组40例）血清40份（各2mL）；急性病毒性脑炎（患者组50例）发病后第1、3、7天各抽取肘静脉血4mL，分离血清。应用谭氏法检测血清中CK—BB的变化。结果患者组CK—BB活性均高于健康对照组（P〈0．01）；发病后第3天CK—BB活性高于第7天和第1天（P〈0．05）；病情进展型病例CK—BB的含量在发病后第1天和第7天高于病情稳定型病例（P〈0．05）；多病灶患者血清CK—BB含量高于单病灶患者（P〈0．05）。结论血清CK—BB可以作为早期诊断急性病毒性脑炎的指标之一，是观察急性病毒性脑炎病情的发展变化、病情严重程度和预后的重要指标之一。

The dynamic change of serous creatine kinase BB(CK-BB)in acute viral encephalitis(AVE)

Objective To observe the dynamic change of serous creatine kinase BB（CK-BB） in acute viral en- cephalitis（AVE）. Methods To get 40 patient serous（each 2 ml） in health person（normal compared group） and get each 4 mL vein blood in the patients with AVE to separate serous after attacking 1,3,7 day. to examine the change of CK-BB in serous by Tan＇s way. Results The living character of patient group is higher than normal compared group. The living character of CK-BB in third day was higher than 7 day and 1 st day（p〈0.05）;The CK-BB content in patients of developing state of illness in third day after attacking were higher than the patients of stable state of illness （p〈0.05） ; The CK-BB in many focus patients（p〈0.05）. Conclusion The content of CK-BB in the serous of patients with AVE is use as one of the targets and is one of the targets to observe the development and change of state of illness of AVE,and is one of the targets to observe serious and prognosis.