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Silver nanoparticles-mediated G2/M cycle arrest of renal epithelial cells is associated with NRF2-GSH signaling
Authors:Kang Su Jin  Lee Young Joon  Lee Eun-Kyung  Kwak Mi-Kyoung
Institution:College of Oriental Medicine, Daegu Haany University, Gyeongsan-si, Gyeongsangbuk-do 712-715, Republic of Korea.
Abstract:
Keywords:nAg  silver nanoparticle  NRF2i  NRF2 knockdown HK-2  SCi  nonspecific control HK-2  scRNA  scrambled RNA  ARE  antioxidant-response element  ROS  reactive oxygen species  GSH  glutathione  NQO1  NAP(D)H:quinone oxidoreductase-1  GCLC  catalytic subunit of γ-glutamate cysteine ligase  GCLM  modulatory subunits of γ-glutamate cysteine ligase  HO-1  heme oxygenase-1  MT  metallothionein  HSP  heat shock protein  SOD  superoxide dismutase  GPX  glutathione peroxidase  MTT  3-(4  5-dimethylthiazol-2-yl)-2  5-diphenyltetrazolium bromide  NAC  N-acetylcysteine  BSO  l-buthionine-[S  R]- sulfoximine  PI  propidium iodide  MN  micronuclei  NDI  nuclear division index  CDC  cell division cycle  CDK  cyclin-dependent kinase
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