| 血管紧张素受体及其拮抗剂与肾脏病关系 |
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| 引用本文： | 杨利才,张道友.血管紧张素受体及其拮抗剂与肾脏病关系[J].中国临床药理学与治疗学,2002,7(2):189-192. |
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| 作者姓名： | 杨利才 张道友 |
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| 作者单位： | 皖南医学院弋矶山医院肾内科,芜湖,241001 |
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| 摘 要： | 肾素血管紧张素系统（RAS）在肾脏病变及其慢性进展中起着非常重要的作用，体内血管紧张素水平升高，可引进血液动力学变化及肾脏分泌众多细胞因子，促进并加重肾脏损害。如何阻断RAS一直是肾脏病学界关注的焦点。近年来随着血管紧张素受体拮抗剂的出现，其与肾脏疾病的关系也日益受到人们的重视。
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| 关 键 词： | 肾脏病 血管紧张素 血管紧张素受体拮抗剂 受体 |
| 文章编号： | 1009-2501(2002)02-0189-04 |
| 修稿时间： | 2001年7月30日 |
Relationship between the angiotensin receptor/antagonist and renal diseases |
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| YANG li-Cai,ZHANG Dao-You.Relationship between the angiotensin receptor/antagonist and renal diseases[J].Chinese Journal of Clinical Pharmacology and Therapeutics,2002,7(2):189-192. |
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| Authors: | YANG li-Cai ZHANG Dao-You |
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| Abstract: | The renin-angiotensin system plays an important role in the pathogenesis and chronic progress of renal diseases. The increased plasma level of angiotensin can induce the changes of haemodynamics and diverse cytokines secreted by the kidney, and the change promotes the renal injury. How to block renin-angiotensin system has been a focus of nephrology. Recently, with the emerging of angiotensin receptor antagonist, the relationship between the angiotensin receptor antagonist and renal diseases has being realized. |
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| Keywords: | renal diseases angiotensin angiotensin receptor antagonist receptor |
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