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青蒿酯钠对微生物作用的实验研究
引用本文:刘碧凤,叶琦莉,赵一. 青蒿酯钠对微生物作用的实验研究[J]. 中国药理学通报, 1986, 0(3)
作者姓名:刘碧凤  叶琦莉  赵一
作者单位:广西中医学院(刘碧凤,叶琦莉),广西中医学院(赵一)
摘    要:本文报道抗疟新药青蒿酯钠对金葡菌、福氏痢疾杆菌、大肠杆菌、卡他球菌、甲型与乙型副伤寒杆菌均有一定的抗菌作用,MIC与MBC为12.5~25mg/ml;对铁锈色小孢子癣菌MIC寿0.0625mg/ml;絮状表皮癣菌MIC为0.5mg/ml;但对流感病毒A_3(京科79—2)与冈比亚锥虫则朱见抑杀作用。

关 键 词:青蒿酯钠  抗微生物活性

EXPERIMENTAL STUDIES ON THE ANTIMICROBIAL ACTI-VITY OF SODIUM ARTESUNATE
LIU Bi-feng YE Qi-li ZHAO Yi. EXPERIMENTAL STUDIES ON THE ANTIMICROBIAL ACTI-VITY OF SODIUM ARTESUNATE[J]. Chinese Pharmacological Bulletin, 1986, 0(3)
Authors:LIU Bi-feng YE Qi-li ZHAO Yi
Affiliation:LIU Bi-feng YE Qi-li ZHAO Yi
Abstract:Experimental studies were made on the antimicrobial action of sodium artesunate. They showed that clinically isolated Gram-positive & Gram-negative microbials, such as S. aureus, S. catarrhalis, S. typhosa, S. paratyphi A & B, Escherichia coli, S. Flexneri were inhibited by Sodium artesunate; its MIC & MBC were 12.5~25 mg/ml. For M. ferrugineum MIC was 0.0625 mg/ml, E. & for floccoum MIC was 0.5 mg/ml, but sodium artesunate exhibited no antivirus & antitrypanosoma activity.
Keywords:Sodium artesunate  antimicrobial activity  
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