| 正交试验优选强心颗粒提取工艺 |
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| 引用本文： | 徐勇. 正交试验优选强心颗粒提取工艺[J]. 光明中医, 2016, 0(16): 2343-2345. DOI: 10.3969/j.issn.1003-8914.2016.16.020 |
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| 作者姓名： | 徐勇 |
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| 作者单位： | 辽宁省本溪市中医院药剂科 本溪 117000 |
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| 摘 要： | 目的优选我院制剂强心颗粒的提取工艺。方法以加水量、煎煮时间和提取次数为考察因素,丹酚酸B含量及干膏率为试验指标,采用L9(3~4)正交试验优选强心颗粒提取工艺。结果强心颗粒最佳提取工艺为8倍水,煎煮1小时,提取2次。结论该研究为强心颗粒剂型改革和制剂工艺研究提供实验依据。
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| 关 键 词： | 正交试验 强心颗粒 提取工艺 丹酚酸B |
Optimization of Extraction Technology of Qiangxin Granules by Orthogonal Experiment |
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| Abstract: | Objective To study the abstraction procedure of Qiangxin granules .Methods The optional extraction process was selected for the yields of extracts&salvianolic acid B by using L 9 (34) orthogonal design .The effects of water addition , duration of decoction and times of extraction were observed .Results The optimal extraction process was determined by 8 times water addition , reflux extracting 2 times, decoction 1 hour.Conclusion The study provided experimental basis for dosage reform and pharmaceutical technology of Qiangxin granules . |
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| Keywords: | Orthogonal experiment Qiangxin granules Extraction technology Salvianolic acid B |
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