| 儿科疾病患儿血清中巯基水平的变化及临床意义探讨 |
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| 引用本文： | 魏倩萍,李眉.儿科疾病患儿血清中巯基水平的变化及临床意义探讨[J].重庆医科大学学报,2000,25(2):192-193. |
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| 作者姓名： | 魏倩萍 李眉 |
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| 作者单位： | 1. 重庆医科大学儿科学院内科,400010
2. 重庆医科大学第二临床学院儿科,400010 |
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| 摘 要： | 目的：探讨自由基在许多疾病具有的重要作用，内源笥物质是抗自由基损伤的重要防御系统之一。方法：观察小儿上感、腹泻和肺炎时血清蛋白巯基（ＰＳＨ）和游离锘（ＮＰＳＨ）的变化。结果：表明肺炎及腹泻患儿血清ＮＰＳＨ明显降低，总巯基和蛋白结合巯基无明显改变。结论：提示腹泻和肺炎时自由基产生可能增加，从而消耗了巯基物质。
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| 关 键 词： | 血清巯基 自由基 儿童 儿科疾病 |
| 文章编号： | 0253-3626(2000)02-0192-02 |
| 修稿时间： | 1999-09-20 |
The clinical significance study of the changes of serum sulfhydry 1 level in children with pediatric diseases |
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| WEI Qian-ping.The clinical significance study of the changes of serum sulfhydry 1 level in children with pediatric diseases[J].Journal of Chongqing Medical University,2000,25(2):192-193. |
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| Authors: | WEI Qian-ping |
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| Institution: | WEI Qian-ping
(Department of Pediatrics, Second College of Clinical Medicine) |
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| Abstract: | Objective:The free radical has a very important effect in many disease process. Interior substance is one of the most important anti-free radical protective system. Methods:This paper investigated the changes of serum protein sulfhydryl (PSH) and non-protein sulfhydryI (NPSH) of children suffering from cold, diarrhea and pneumonia. Results:The serum NPSH decreases markedly in children with diarrhea and pneumonia, the total sulfhydryl and protein bind sulfhydryl do not change obviously. Conclusion:This research suggests that free radical may increase in pneumonia and diarrhea that wastes the sulfhydryl substances. |
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| Keywords: | Sulfhydryl Infection Free radical |
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