| 米托蒽醌治疗小儿难治复发的急性非淋巴细胞白血病的临床研究 |
| |
| 引用本文： | 关智勇.米托蒽醌治疗小儿难治复发的急性非淋巴细胞白血病的临床研究[J].中国小儿血液与肿瘤杂志,2001,6(4):148-149. |
| |
| 作者姓名： | 关智勇 |
| |
| 作者单位： | 深圳市罗湖区妇幼保健院,519019 |
| |
| 摘 要： | 为探讨小儿难治复发的急性非淋巴细胞白血病的治疗方法 ,临床上观察了 2 7例病人 ,经米托蒽酯 6mg/m2 × 3天 ,Ara c 1 50mg/m2 × 7天 ,VP166 0mg/m2 × 5天的联合化疗疗效。结果治疗后CR 37% ( 1 0 /2 7) ,PR 30 % ( 8/2 7) ,总有效率 6 7% ,化疗后骨髓造血功能抑制明显 ,感染发生率较高为 73% ,结果显示 :以米托蒽醌为主的化疗治疗小儿难治及复发的急性非淋巴细胞白血病有较好疗效。
|
| 关 键 词： | 急性非淋巴细胞白血病 难治 复发 米托蒽醌 |
Studeies on the treatment of mitoxantrone in children with refractory and recurrent acute non-lymphocytic leukemia |
| |
| Abstract: | To explore the therapeutic effects of Mitoxantrone with Ara-C and VP-16 in treating refractory, recurrent acute non-lymphocytic leukemia in children, 27-case of refractory, recurvent pediatric ANLL were selected and observed clinically. All underwent a combined chemotherapy regimen of Mitoxantrone (6mg/m 2×3d), Ara-C (150mg/m 2×7d), VP-16 (60mg/m 2×5d). Results: complete remission 37%, partial remission 30%, the total effective rate was 67%, inhibition of bone marrow was obvious, infection rate was 73%. Conclusion: Mitoxantrone regimen was an effective chemotherapy regimen for refractory, recurrent ANLL in Children,provided adequate supporting treatment for bone marrow. |
| |
| Keywords: | |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
