舒血宁注射液治疗慢性肺原性心脏病急性加重期临床研究

目的研究舒血宁注射液治疗慢性肺原性心脏病(肺心病)急性加重期临床疗效。方法将80例慢性肺心病急性加重期患者随机分为2组,对照组40例,采用西医常规治疗,治疗组40例在此基础上,加用舒血宁注射液20ml,静脉滴注,qd,7d1疗程,共2疗程。结果治疗组显效率、总有效率分别为45.0%、90.0%,对照组为20.0%、67.5%,2组比较差异有显著性意义(P<0.05)。治疗组临床指标恢复正常时间、血流变学、动脉血气分析均优于对照组(P<0.05)。结论舒血宁注射液治疗慢性肺心病急性加重期可提高临床疗效,缩短治疗时间。

The effect of Shuxuening injection on the treatment of chronic cor pulmonale in acute exacerbation

Objective To study clinical therapeutic effect of Shuxuening on treatment of chronic cor pulmonale in acute exacerbation.Methods Eighty patients with chronic cor pulmonale in acute exacerbation were randomly diveded into 2 groups.The control group(n=40) was treated with routine western medicine.The therapeutic group(n =40) was treated with routine western medicine plus Shuxuening injection.the course of treatment was 7 day.All treated for 2 courses of treatment.Results The obvious effective rate and the total effective rate were 45.0% and 90.0% respectively in therapeutic group,and they were 20.0% and 67.5% respectively in controt group(P<0.05).Therapeutic group surpasses control group in recovering normal time of clinical indexes,hemorheology indexes and blood gas analysis after treatment(all P<0.05).Conclusions Shuxuening injection may improve therapeutic effects and short curative time of chronic cor pulmonale in acute exaccerbation.