| 克拉霉素治疗慢性阻塞性肺疾病急性加剧期50例 |
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| 引用本文： | 任少华. 克拉霉素治疗慢性阻塞性肺疾病急性加剧期50例[J]. 中国新药杂志, 2001, 10(2): 122-124 |
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| 作者姓名： | 任少华 |
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| 作者单位： | 浙江省丽水市中心医院, |
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| 摘 要： | 目的：对照观察口服克拉霉素与静注氨苄青霉素＋舒巴坦钠治疗慢性阻塞性肺疾病（COPD）急性加剧期的疗效与不良反应。方法：将50例COPD急性加剧期患者随机分为2组，每组均为25例，治疗组口服克拉霉素0．5g,bid，对照组静注氨苄青霉素＋舒巴坦钠1．5g,bid。结果：治疗组的有效率为92％，对照组的有效率为72．2％，不良反应发生率2组均为8％。结论：克拉霉素治疗COPD急性加剧期的临床疗效，病原菌覆盖面广，使用方便。
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| 关 键 词： | 克拉霉素 下呼吸道感染 慢性阻塞性肺病 |
| 文章编号： | 1003-3734(2001)02-0122-03 |
The efficacy of clarithromycin in treatment of a cute exacerbationof COPD(chronic obstructive pulmonary disease)in 50 cases |
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| REN Shao-hua. The efficacy of clarithromycin in treatment of a cute exacerbationof COPD(chronic obstructive pulmonary disease)in 50 cases[J]. Chinese Journal of New Drugs, 2001, 10(2): 122-124 |
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| Authors: | REN Shao-hua |
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| Abstract: | Objective:To compare the efficacy and side effect of clarithromycin and ampecillin-sulbactum in treatment of acute exacerbation of COPD.Methods:50 acute exacebation patients of COPD were randomly a nd equally divided to receive twice daily 0.5g oral clarithromycin or twice dail y 1.5g ampecillin-sulbactum infusion.Results:The total effective rate for clarithromycin and ampecillin-sulbactum group was 92% and 72.2% respec tively with a side effect rate of 8% in both groups.Conclusion:Cla rithromycin is an ideal agent for treatment of acute exacerbation of COPD with t he advantages of convenience and broad anti-bacterial spectrum. |
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| Keywords: | Clarithromycin lower respiratory tract infection ch ronic obstructive pulmonary disease(COPD). |
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