21例原发女性尿道癌临床分析

[目的]探讨原发性女性尿道癌的临床特点、治疗及预后。[方法]回顾性分析21例原发性尿道癌临床资料。[结果]原发性女性尿道癌好发于中老年，平均年龄54岁，全部病灶见于尿道口，以尿道口肿物、尿路刺激症为主要表现，病理以腺癌和鳞癌多见，放射和手术为主要治疗方式。生存时间6天-273个月，早期病例及鳞癌预后较好，晚期病例及腺癌和移行上皮癌预后较差。[结论]原发女性尿道癌的预后与分期、病理类型，治疗方法有关。

Clinical Analysis of 21 Cases with Primary Female Urethral Carcinoma

To investigate the clinical characteristics,treatment and prognosis of primary female urethral carcinoma. The hospital records of 21 women with primary urethral carcinoma were retrospectively reviewed. Primary female urethral carcinoma was more frequently seen in middle aged and old women,average 54 years of age.All cases originated from the external orifice of urethra.The main clinical features were neoplasm of external urethral orifice and urethra irritated symptoms.The common pathological types were squamous cell carcinoma.The main treatments were radiation and operation.The survival times were 6 days to 273 months .The patients prognosis in early stage or with squamous cell carcinoma had better prognosis, and in advanced stage or with adenocarcinoma and transition carcinoma had worse prognosis.[Conclusion] The prognosis of primary female urethral carcinoma are associated with clinical stage,pathological type and modality of therapy.