| 妊娠与非妊娠大鼠子宫内膜促性腺激素释放激素及其受体的免疫组织化学研究 |
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| 引用本文： | 夏永娟,黄威权. 妊娠与非妊娠大鼠子宫内膜促性腺激素释放激素及其受体的免疫组织化学研究[J]. 解剖学杂志, 2001, 24(1): 33-36 |
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| 作者姓名： | 夏永娟 黄威权 |
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| 作者单位： | 第四军医大学组织学与胚胎学教研室, |
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| 摘 要： | 目的：研究促性腺激素释放激素（GnRH)及其受体在妊娠与非妊娠大鼠子宫内膜中的分布及相对含量，为了解促性腺激素释放激素对子宫内膜的可能功能提供依据。方法：免疫组织化学ABC法及图像分析技术。结果：非妊娠大鼠子宫内促性腺激素释放激素及促性腺激素释放激素受体阳性反应发生在内膜上皮、腺上皮及基质细胞。妊娠大鼠子宫内这二者阳性反应主要发生在内膜上皮及基蜕膜的蜕膜细胞，妊娠大鼠子宫上皮细胞中的促性腺激素释放激素及其受体的相对含量明显高于非妊娠大鼠子宫内膜。结论：妊娠与非妊娠大鼠子宫内膜均能表达促性腺激素释放激素及其受体。
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| 关 键 词： | 子宫内膜 促性腺激素释放激素 受体 免疫组织化学 妊娠 |
IMMUNOHISTOCHEMICAL LOCALIZATION OF GnRH AND GnRH RECEPTOR IN THE ENDOMETRIUM OF PREGNANT RATS AND UNPREGNANT RATS |
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| Xia Yongjuan,Huang Weiquan. IMMUNOHISTOCHEMICAL LOCALIZATION OF GnRH AND GnRH RECEPTOR IN THE ENDOMETRIUM OF PREGNANT RATS AND UNPREGNANT RATS[J]. Chinese Journal of Anatomy, 2001, 24(1): 33-36 |
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| Authors: | Xia Yongjuan Huang Weiquan |
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| Abstract: | Objective: To study the distribution and relative contents of GnRH and GnRH receptor in the endometrium in pregnant rats and unpregnant rat. Methods: Immunohistochemical ABC method and image analysis were used in the experiment. Results: GnRH and GnRH recepter positive immunoreaction occured in the endometrium epithelium and the glandular epithelium of unpregnant rats, and in the endometrium epithelium and deciduate cells of the basal decidua of rpegnant rat. Conclusion: The GnRH may take part in regulating endometrial function through its receptor, its effect on endometrium may be strong in pregnant uterine than in unpregnant. |
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| Keywords: | uterus endometrium gonadotropin-releasing hormone receptor |
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