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Identification of human chorionic gonadotropin (HCG) secreting cells and other cell types using antibody to HCG and a new monoclonal antibody (mABlu-5) in cultures of human placental villi
Authors:M Frauli  H Ludwig
Institution:(1) Department of Obstetrics and Gynecology, University of Basle, Switzerland;(2) Universitäts-Frauenklinik, Schanzenstrasse 46, CH-4031 Basle, Switzerland
Abstract:Summary We have identified cells which secrete human chorionic gonadotropin (HCG) of cultures if first trimester placental villi. As a first step, we identified epithelial cells using a new monoclonal antibody. We then added HCG antibodies to the cultured cells. We found that syncytiotrophoblast (and not cytotrophoblast), Hofbauer cells and some mesenchymal cells stained with HCG antibodies.
Keywords:HCG  Monoclonal antibody lu-5 (mABlu-5)  Cultures  Human placenta
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