Monocyte chemoattractant protein-1 (MCP1) promoter -2518 polymorphism may confer a susceptibility to major depressive disorder in the Korean population |
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| Authors: | Pae Chi-Un Yu Hye-Sook Kim Tae-Suk Lee Chang-Uk Lee Soo-Jung Jun Tae-Youn Lee Chul Serretti Alessandro Paik In-Ho |
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| Affiliation: | Department of Psychiatry, Kangnam St. Mary's Hospital, Catholic University of Korea College of Medicine, 505 Banpo-Dong, Seocho-Gu, Seoul 137-701, Republic of Korea. |
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| Abstract: | We conducted a case-control association study of the monocyte chemoattractant protein-1 (MCP1) gene -2518 polymorphism in 90 patients with major depressive disorder. Genotyping was performed by polymerase chain reaction methods. We found significant differences in genotype and allele frequencies. The present study suggests that this polymorphism may confer a susceptibility to major depressive disorder in the Korean population. |
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