Onset and offset pharmacodynamics of propofol |
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| Authors: | O'Halloran P L Hosseini-Yeganeh M McBride L J Ramzan I |
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| Institution: | Faculty of Pharmacy, University of Sydney, NSW, Australia. |
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| Abstract: | Propofol whole blood and plasma concentrations at offset of hypnosis in eighteen patients were inversely related to patient age and body fat. The relationship between propofol concentrations and body fat is derived from the relationship between age and body fat and age was the single independent predictor of concentrations at offset of propofol hypnosis. |
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