正交试验优选温阳通便颗粒中挥发油提取工艺

目的优选温阳通便颗粒中当归、肉桂挥发油的最佳提取工艺条件。方法采用水蒸气蒸馏轻油装置加乙醚萃取的方法提取当归、肉桂挥发油,以挥发油收率作为评价指标,选择浸泡时间、加水量及提取时间为主要影响因素,应用L9(34)正交试验设计,选取最佳提取工艺条件。结果水蒸气蒸馏法提取当归、肉桂挥发油的最佳工艺条件为:药材浸泡3 h,加10倍量水,蒸馏提取6 h。结论本试验优选所得提取工艺条件稳定可行。

Optimization of Extraction Process of Volatile Oil from Wenyang Purgation Granules by Orthogonal Design

Objective To optimize the extraction conditions of volatile oil from Angelica Sinensis and Cassia Bark in Wenyang purgation granules. Methods The volatile oil was extracted from Angelica Sinensis and Cassia Bark by the method of steam distillation light oil device with diethyl ether extraction. The yield of the volatile oil was chosen as the evaluation index. The time of dip in water, the ratio of water to herbal medicine material and the time of distillation were used as the main factors. The optimum extraction conditions were investigated by the L9（3^4） orthogonal design. Results The optimal conditions for extraction process of volatile oil from Angelica Sinensis and Cassia Bark in Wenyang purgation granules were as follows： the time of dip in water was 3 h; the ratio of water to herbal medicine material was 10 ： 1; the time of distillation was 6 h. Conclusion The optimized conditions of extraction process are stable and feasible.