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| 引用本文： | 孙英贤.??????????????????????[J].中国实用内科杂志,2009,29(1):14. |
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| 作者姓名： | 孙英贤 |
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| 作者单位： | 中国医科大学盛京医院心内科,沈阳,110001
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| 摘 要： | 新型胆固醇吸收抑制剂依哲麦布(ezetimihe,EZ)可显著降低患者的低密度脂蛋白胆固醇(LDL-C),升高高密度脂蛋白胆固醇(HDL-C)水平,不良反应较少.EZ与他汀类药物联合应用,有良好的药物协同效应,可避免大剂量他汀潜在的不良反应.如果患者在单用最佳剂量他汀类治疗的情况下没有达标,那么EZ联合他汀类可以是一种合理的治疗.
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| 关 键 词： | 降血脂药 高胆固醇血症 胆固醇吸收抑制剂 依哲麦布 |
Clinical application of cholesterol absorption inhibitor |
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| SUN Ying-xian.Clinical application of cholesterol absorption inhibitor[J].Chinese Journal of Practical Internal Medicine,2009,29(1):14. |
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| Authors: | SUN Ying-xian |
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| Abstract: | ??The new cholesterol absorption inhibitor Ezetimibe (EZ) could markedly reduce the LDL??C level and increase the HDL??C level with little adverse effect.EZ combined with statins shows cooperative effect and avoids the latent adverse effect of large dose of statins.Thus this combined therapy is a reasonable choice for the patients whose cholesterol level could not reach the standard after using optimum dose of statins. |
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