| 双抗体夹心法检测血清S-100蛋白及其临床意义 |
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| 引用本文： | 裴惠临,郭清莲. 双抗体夹心法检测血清S-100蛋白及其临床意义[J]. 武汉大学学报(医学版), 2004, 25(1): 72-73 |
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| 作者姓名： | 裴惠临 郭清莲 |
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| 作者单位： | 武汉大学中南医院检验科,武汉,403371;武汉大学中南医院检验科,武汉,403371 |
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| 摘 要： | 目的 :为研究血清中S 1 0 0蛋白与脑组织病变的关系。方法 :采用S 1 0 0蛋白单克隆抗体为包被抗体和抗S 1 0 0多克隆抗体为检测抗体的双抗体夹心ELISA方法 ,检验神经系统损伤及脑肿瘤组与正常对照组 (无神经系统损伤、无肿瘤 )的血清中S 1 0 0的含量。结果 :神经系统损伤患者S 1 0 0蛋白大多 >0 .1 5 μg·L-1 ,正常对照组 <0 .1 5 μg·L-1 ,差别有显著性。结论 :S 1 0 0蛋白可作为衡量脑组织病变 (脑损伤、脑肿瘤 )的一个临床指标 ,尤其在脑损伤累及神经胶质细胞后
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| 关 键 词： | S-100蛋白 血清 神经胶质细胞 |
| 文章编号： | 1671-8852(2004)01-0072-02 |
| 修稿时间： | 2003-03-11 |
Detection of S100-Protein in Serum by Elisa and Its Clinical Significance |
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| Pei Huilin,Guo Qinglian. Detection of S100-Protein in Serum by Elisa and Its Clinical Significance[J]. Medical Journal of Wuhan University, 2004, 25(1): 72-73 |
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| Authors: | Pei Huilin Guo Qinglian |
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| Affiliation: | Pei Huilin,Guo Qinglian Department of Clinical Laboratory,Zhongnan Hospital,Wuhan University,Wuhan 430071,China |
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| Abstract: | Objective: To determine the relationship between S 100 protein and the brain injury.Methods: Two antibody sandwich ELISA was used to detect the concentration of S 100 protein in serum. Results: The content of S 100 protein in patients with brain injury or tumor was mostly higher than 0.15 μg·L -1 , which is the normal content in health.Conclusion: In conclusion, S 100 protein can be used as a useful index to diagnose the lesion of brain. |
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| Keywords: | S 100 protein serum neuroglial cell |
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