In Vitro Studies with Cefazolin |
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| Authors: | Milwood Motley and Smith Shadomy |
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| Affiliation: | .Department of Microbiology, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia 23298;.Department of Medicine, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia 23298 |
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| Abstract: | Susceptibilities of 259 isolates of pathogenic bacteria to cefazolin were measured by broth and agar dilution procedures. Beta-hemolytic streptococci were inhibited by 0.25 mug/ml, whereas Staphylococcus aureus and alphahemolytic streptococci were inhibited by 2.0 mug/ml. Enterococci were resistant to less than 32 mug/ml. Wide variation was seen with gram-negative species. Most isolates of Klebsiella species and Proteus mirabilis were inhibited by 4.0 or 8.0 mug/ml. Escherichia coli were less susceptible, and most isolates of Pseudomonas aeruginosa, Serratia species, and Enterobacter species were resistant to 128 mug/ml. |
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