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寻常性银屑病肾脏损伤与PASI评分的关系
引用本文:楚瑞琦,刘辉,王咏梅,石宁,孙力,赵建伟,刘春梅,沈俊萍.寻常性银屑病肾脏损伤与PASI评分的关系[J].中国皮肤性病学杂志,2010,24(9).
作者姓名:楚瑞琦  刘辉  王咏梅  石宁  孙力  赵建伟  刘春梅  沈俊萍
作者单位:1. 河北大学附属医院皮肤科,河北,保定,071000
2. 河北大学流行病学教研室,河北,保定,071000
3. 河北大学附属医院肾内科,河北,保定,071000
4. 河北大学附属医院核医学科,河北,保定,071000
摘    要:目的探讨银屑病皮损面积和严重程度与银屑病肾损伤的关系。方法采用Spearman秩对114例银屑病患者进行尿Alb,尿IgG,尿β2-MG与皮肤损害面积和皮肤损伤程度进行相关分析。结果构成PASI的红斑、浸润、鳞屑、面积四项因素均与尿微球蛋白不相关,而4项因素均与尿球蛋白具有相关性,红斑、浸润、鳞屑3项因素与尿白蛋白具有相关性。结论肾小球损伤与PASI相关密切,尤其是红斑与肾小球结构性损伤相关性更为密切。

关 键 词:银屑病  银屑病肾损伤  PASI

Relation of PASI Score and Psoriasis Renal Injury
CHU Rui-qi,LIU Hui,WANG Yong-mei,SHI Ning,SUN Li,ZHAO Jian-wei,LIU Chun-mei,SHEN Jun-ping.Relation of PASI Score and Psoriasis Renal Injury[J].The Chinese Journal of Dermatovenereology,2010,24(9).
Authors:CHU Rui-qi  LIU Hui  WANG Yong-mei  SHI Ning  SUN Li  ZHAO Jian-wei  LIU Chun-mei  SHEN Jun-ping
Abstract:Objective To study the relation of PASI score and psoriasis renal injury. Methods The urine Alb,urine IgG and urine β2-MG of 114 cases with psoriasis were studied. Statistical analyses were performed using spearman rank correlation to evaluate the relation of PASI and psoriasis renal injury. Results The urine β2-MG were not affected by erythema,infiltration,scale and skin lesion area of PASI. The urine IgG were affected by erythema,infiltration,scale and skin lesion area of PASI. The urine Alb were affected by erythema,infiltration and scale of PASI. Conclusion The renal glomerulus may be affected by PASI,especially,the structural lesion of renal glomerulus may obviously be affected by the erythema.
Keywords:PASI
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