Characterization of a <Emphasis Type="Italic">Pestivirus H</Emphasis> isolate originating from goats |
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| Authors: | " target="_blank">Hongfei Shi Chaoliang Leng Qian Xu Hongling Shi Shiyu Sun Yunchao Kan Lunguang Yao |
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| Institution: | 1.Henan Provincial Engineering Laboratory of Insects Bio-reactor,China-UK-NYNU-RRes Joint Libratory of Insect Biology, Nanyang Normal University,Nanyang,People’s Republic of China;2.Liaoning Center for Animal Disease Control and Prevention,Shenyang,People’s Republic of China |
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| Abstract: | Natural Pestivirus H infections in cattle have been reported worldwide; however, only a few cases of Pestivirus H have been described in non-bovine ruminants such as goats. A new Pestivirus H HN1507 strain was isolated from an infected goat in 2015 and the genome sequence was determined. The full-length genome sequence was 12,556 nucleotides. Phylogenetic analysis, based on the complete genome and Npro fragments, revealed that the isolate belonged to Pestivirus H and was closely related to strains from Italy. Two unique amino acid substitutions were found in the C-terminal of the E2 protein. To the best of our knowledge, this is first report determining the complete genome of a Pestivirus H strain from goat. |
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