| 急性排斥反应时CD15和血小板/内皮细胞粘附分子在移植肾的表达 |
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| 引用本文： | 郭颖,郭琳琅,高伟.急性排斥反应时CD15和血小板/内皮细胞粘附分子在移植肾的表达[J].中华器官移植杂志,1998,19(3):143-145. |
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| 作者姓名： | 郭颖 郭琳琅 高伟 |
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| 作者单位： | 1. 第一军医大学附属珠江医院肾移植科,广州,510282
2. 第一军医大学附属珠江医院病理科,广州,510282 |
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| 摘 要： | 应用免疫组织化学ＳＰ法和计算机图象分析系统观察分析了１８例急性排斥反应时移植肾活检标本中ＣＤ１５和血小板／内皮细胞粘附分子的表达情况，以探讨其变化的意义。
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| 关 键 词： | 肾移植 免疫因子 免疫测定 排斥反应 |
Cell adhesion molecule CD15 and PECAM-1 in renal tissue during acute allograft rejection and their implication |
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| Guo Ying,Guo Linlang,Gao Wei.Cell adhesion molecule CD15 and PECAM-1 in renal tissue during acute allograft rejection and their implication[J].Chinese Journal of Organ Transplantation,1998,19(3):143-145. |
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| Authors: | Guo Ying Guo Linlang Gao Wei |
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| Abstract: | The changes in cell adhesion molecule CD15 and PECAM-1 in grafted renal tissue from 18 cases of acute allograft rejection were studied by immunohistochemistry techniques (SP method ) and computerized imaging analysis system. The results showed that: (1) CD15 positive expression level was higher in acute allograft rejection than that in normal renal in tuberular cells.(2) PECAM-1 expression level was lower in glomerular endothelial cells, but higher in tuberular cells than those in normal renal tissue during acute allograft rejection. The above findings suggested that the detection of CD15 and PECAM-1 in the grafted kidney might have some values in the diagnosis of acute allograft rejection. |
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| Keywords: | Kidney Transplantation Immunologic factors Immunoassay |
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