Pharmacologic treatment of fibromyalgia |
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Authors: | André Barkhuizen MD |
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Institution: | (1) Department of Medicine (L329A), Oregon Health Sciences University and Portland VA Medical Center, 3181 SW Sam Jackson Park Road, 97201 Portland, OR, USA |
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Abstract: | Fibromyalgia is a chronic syndrome characterized by widespread pain, unrefreshed sleep, disturbed mood, and fatigue. Until
such time as we have a clearer understanding of the trigger and/or pathophysiologic mechanisms producing these symptoms, pharmacologic
treatment should be aimed at individual symptoms. Such treatment should ideally be offered as part of a multidisciplinary
treatment program using both pharmacologic and nonpharmacologic treatment modalities.
Critical components of any successful fibromyalgia treatment program include addressing physical fitness, work and other functional
activities, and mental health, in addition to symptom-specific therapies. The main symptoms that should be addressed include
pain, sleep disturbances including restless leg syndrome, mood disturbances, and fatigue. Pharmacologic therapy should also
be considered for syndromes commonly associated with fibromyalgia including irritable bowel syndrome, interstitial cystitis,
migraine headaches, temporomandibular joint dysfunction, dysequilibrium including neurally mediated hypotension, sicca syndrome,
and growth hormone deficiency. This article provides general guidelines in initiating a successful pharmacologic treatment
program for fibromyalgia. |
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