中药复方对冠心病治疗性血管新生的临床分析 |
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引用本文: | 秦立,石海莉,黄捷,宋昆鹏,李艳,白起君. 中药复方对冠心病治疗性血管新生的临床分析[J]. 中医临床研究, 2014, 0(31): 22-23 |
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作者姓名: | 秦立 石海莉 黄捷 宋昆鹏 李艳 白起君 |
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作者单位: | 郑州大学附属郑州中心医院,河南郑州450000 |
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摘 要: | 目的:观察并探讨中药复方对冠心病治疗性血管新生的作用。方法:选择实验用大鼠30只作为本次实验对象,将大鼠随机分为观察1组、观察2组与对照组3组,每组10只。观察1组作为中药组,观察2组为贝复济组,对照组为空白组。作大鼠心肌缺血实验模型,术后分别给药,观察3组大鼠EC、CD、VEGF及bFGF表达。结果:观察1组、观察2组大鼠CD与EC分布且与对照组比较,具有显著性差异(P〈0.05);观察1组与观察2组VEGF及bFGF反应与对照组比较,结果具有显著性差异(P〈0.05)。结论:中药复方可促进冠心病治疗性血管新生作用,其在临床上的应用还有待于进一步临床验证。
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关 键 词: | 中药复方 冠心病 治疗性血管新生 |
A clinical analysis of treating coronary heart disease therapeutic angiogenesis in TCM medicine |
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Abstract: | Objective:To observe and analyze clinical effects of TCM medicine on coronary heart disease therapeutic angiogenesis. Methods:30 rats were randomly divided into the observation group 1 (TCM medicine group), the observation group 2 (bFGF group) and the control group (blank group). Myocardial ischemia modes were made, EC,CD, VEGF and bFGF expression of rats in three groups were observed. Results: CD, EC distribution in the observation 1 and the observation 2 has statistically significant compared with the control group (P〈0.05);the same as VEGF and bFGF reactions (P〈0.05). Conclusion:TCM medicine can improve the function of coronary heart disease therapeutic angiogenesis, its application needs more examination. |
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Keywords: | TCM combined medicine Coronary heart disease Therapeutic angiogenesis |
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