不同压力高压氧对颅脑外伤术后昏迷患者的早期治疗 |
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引用本文: | 何春阳,吴帆,付西,邓韩彬,蒙俊甫,刘毅,呼永河.不同压力高压氧对颅脑外伤术后昏迷患者的早期治疗[J].西南军医,2013(6):601-603. |
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作者姓名: | 何春阳 吴帆 付西 邓韩彬 蒙俊甫 刘毅 呼永河 |
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作者单位: | [1]成都军区总医院,成都610083 [2]四川省计算机研究院,成都 |
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摘 要: | 目的:观察不同压力高压氧(HBO)对颅脑外伤术后昏迷患者的早期疗效。方法按入组先后顺序随机将75例颅脑外伤术后昏迷患者分为对照组、0.20MPa高压氧组(HBO1组)和0.25MPa高压氧组(HBO2组),每组25例,比较三组患者在术后1周内和术后1月的格拉斯哥昏迷评分(GCS),以及出院前的治愈显效率。结果(1)三组患者在术后1周内GCS评分无统计学差异(P〉0.05),但治疗1月后GCS评分均提高(P〈0.05)。(2)治疗后HBO1组和HBO2组GCS评分明显高于对照组,且HBO2组评分高于HBO1组(P〈0.05)。(3) HBO1组和HBO2组的治愈显效率(76%和80%)明显高于对照组(48%)(P〈0.05),但HBO1组和HBO2组之间无统计学差异(P〉0.05)。结论早期两种压力的HBO治疗对颅脑外伤术后昏迷患者的恢复均有良好促进作用,其中0.25MPa压力的HBO对患者的促醒作用可能更优。
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关 键 词: | 高压氧 治疗压力 颅脑外伤 格拉斯哥昏迷评分 |
Hyperbaric Oxygen at Different Pressure as Early Treatment for Post-operative Coma of Patients with Cerebral Trauma |
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Authors: | He Chunyang Wu Fan Fu Xi Deng Hanbin Meng Junfu Liu Yi Hu Yonghe |
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Institution: | , Department ofHBO, Chengdu Military General Hospital, Chengdu, Sichuan Province, 610083, P. R. China |
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Abstract: | Objective To observe the curative effect of hyperbaric oxygen (HBO) at different pressure as the early treatment on post-operative coma of patients with cerebral trauma. Methods 75 cases with cerebral trauma suffering from post-operative coma were randomly divided into 3 groups:HBO group 1 (at 0.20MPa),HBO group 2 (at 0.25MPa) and control group,25 in each;a comparative study was made to the Glasgow coma scores (GCS) of the patients in the 3 groups at 1 week and at 1 month after operation,as well as to the cured and obvious effective rate before discharge. Results There existed no statistical difference among the GCS at 1 week after operation of the patients in the 3 groups (P〉0.05) while their scores all increased at 1 month after operation (P〈0.05);the scores of HBO group 1 and HBO group 2 were both higher than that of control group after treatment,and the scores of HBO group 2 were higher than that of HBO group 1 (P〈0.05);the obvious effective rates of HBO group 1 and HBO group 2 (76%and 80%) were significantly higher than that of control group (48%) (P〈0.05) while no statistical difference was found between the rates of HBO group 1 and HBO group 2 (P〉0.05). Conclusions Early treatment of HBO at two different pressures is of good effect on the recovery of patients with cerebral trau-ma suffering from post-operative coma,and HBO treatment at the pressure of 0.25MPa may be of more superior effect. |
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Keywords: | hyperbaric oxygen (HBO) therapeutic pressure cerebral traumaGlasgow coma score (GCS) |
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