36例急性一氧化碳中毒后迟发性脑病的P300电位分析

目的　了解急性一氧化碳中毒后迟发性脑病与 P30 0电位之间的联系 ,为诊疗本病提供更多的依据。方法　对 36例急性一氧化碳中毒后迟发性脑病患者与 4 0例健康者分别进行了 P30 0测定和智商测定 ,并将两组结果进行了比较。结果　患病组与对照组比较 ,P30 0电位成份中 N2、P3潜伏期延长 ,P3波幅降低与对照组存在显著性差异 ( P<0 .0 1 )。智商测定中 1 1分量表得分低于对照组 ,存在显著性差异 ( P<0 .0 1或 P<0 .0 5 )。结论　P30 0电位对急性一氧化碳中毒后迟发性脑病的认知功能及疗效判定有一定的价值。

The Analysis on P300 Potentials of 36 Patients with Delayed Encephalopathy after Acute Monoxide Poisoning

Objective To explore the relations between P300 Potentials and delayed encephalopathy after acute carbon monoxide poisoning(DEACMP)in order to provide more methods for diagnosing and treating the disease.Methods 36 Patients with DEACMP and 40 controls were determined respectively with P300 potentials and Wechsler Adult Intelligence Scale(WAIS).The results of 36 patients with DEACMP were compared with those of 40 controls.Results Latent period of N2 and P3 of P300 potentials in 36 patients with DEACMP were longer than those in the controls and amplitude of P3 of P300 potentals in the patients was lower than that in the controls.These were significantly difference between the two groups(P<0.01 or P<0.05).Conclusion P300 potentials has remarkable value in evaluating cognition function and effect of treatment on the patients with DEACMP.