复方苦参注射液在食管癌及胃癌术后化疗中的应用观察

目的：观察复方苦参注射液在食管癌及胃癌术后化疗中的作用。方法：实验组应用常规化疗方案加复方苦参注射液静脉滴注，对照组应用常规化疗方案，三周为一疗程，计六个疗程。结果：实验组疗效优于对照组，恶心，呕吐，肝肾功能损害发生率明显低于对照组（P〈0．05）。实验组化疗后KPS评分有不同程度上升，但无明显差异，而对照组治疗后KPS评分降低，且有明显差异（P〈0．05）。实验组化疗后白细胞变化无明显差异（P〉0．05）。对照组化疗前后白细胞下降明显（P〈0．05）。结论：复方苦参注射液可提高上消化道肿瘤术后化疗的疗效，显著减轻化疗的毒副反应，提高患者生活质量。

Study of Composite Kushen Injection in Postoperative Chemotherapy of Gastric and Esophageal Cancer

Objective： To evaluate the therapeutic efficiency of composite Kushen injection in postoperative chemotherapy of gastric and esophageal cancer. Methods： The test group was treated with routine chemotherapy programme and intravenous drop of composite Kushen injection. At the same time, the control group only received routine chemotherapy programme. The therapy in both groups lasted for six courses of treatment, which included three weeks of chemotherapy. Results： The incidence rates of nausea, vomit and hepatic injury in test group were lower than the control group （P〈0.05）. After chemotherapy, the KPS of test group increased while the KPS of control group was lower （P〈0.05）. After chemotherapy the change of WBC in test group was not apparent （P〉0.05） but the WBC reduced apparently in control group （P〈0.05）.Conclusions： The application of composite Kushen injection in gastric and esophageal cancer can decrease the side effect of chemotherapy apparently.