高血压性左室肥厚患者的校正QT间期离散度变化及临床意义

目的：研究高血压性左室肥厚患者的ＱＴｃｄｅ变化及临床意义。方法；采用１２导联心电图同步记录，超声检查一动态心电图监测５６例高血压患者的ＱＴｃｄ，心脏形态和心律失常。结果：高血压病组和对照组间ＱＴｃｄ差异非常显著，高血压伴ＬＶＨ组和室性心律失常组的ＱＴｃｄ均显著长于无伴ＬＶＨ组和或无ＶＡｓ组；ＬＶＨ组ＶＡｓ和复杂型心律失常发生率均显著高于无ＬＶＨ组。

Changes and clinical significance of corrected QT dispersion in hypertensive patients with left ventricular hypertrophy

AIM:To study the changes and clinical significance of QTcd in hypertensive left ventricular hypertrophy (LVH).METHODS:QTcd, cardiac shape and VAs were measured by electrocardiography at rest, colour doppler echocardiography and 24 h ambulatory electrocardiography were observed in 56 patients with hypertension.RESULTS:QTcd was significantly prolonged in hypertensive patients compared with control group, and it is clinically important that QTcd had obvious differences between LVH and without LVH or VAs and without VAs. The incidences of VAs and complex VAs in 27 cases with LVH were significantly higher than that in 29 cases without LVH.CONCLUSION:There is marked imbalance in the repolarization of myoardium and instability of cardiac electrical activity in hypertensive patients, particularly with LVH and/or VAs. There is a positive correlation between QTcd, LVH and VAs; QTcd may be an indication of complex ventricular arrhythmia risk in patients with hypertensive LVH.