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Autobiographical memory in progressive supranuclear palsy
Authors:M. Zarei  H. R. Pouretemad  T. Bak  J. R. Hodges
Affiliation:1. Department of Clinical Neurology, University of Oxford, Oxford, UK;2. Department of Psychology, Shahid Beheshti University, Tehran, Iran;3. Department of Psychology, University of Edinburgh, Edinburgh, UK;4. Prince of Wales Medical Research Institute, Sydney, Australia
Abstract:Background: We aimed to investigate recall of autobiographical memories across lifetime periods in patients with progressive supranuclear palsy (PSP). Method: Patients with PSP (n = 10) were given a test of autobiographical and personal semantic information and the Addenbrooke’s Cognitive Examination (ACE). The result was compared to 30 matched neurologically intact participants. Result: A mild autobiographical memory impairment was observed in PSP without a temporal gradient for the recall of autobiographical or personal semantic information. Performance correlated with verbal fluency in ACE. Conclusion: Patients with PSP show mild deficits in autobiographical memory, which is likely to reflect a frontal retrieval deficit.
Keywords:autobiographic memory  progressive supranuclear palsy
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